TRANSPORT : Explain the mechanism of blood clotting

Mechanism of blood clotting

Blood Clotting For Minor Wound 

Connective tissue : located in a vessel wall is cut and exposed to the blood.

Platelets : The aggregation of platelets forms a plug. Platelet will stick rapidly.

Platelet Plug

: It can stop the blood loss completely if the damage to  the vessel is small.

Blood Clotting For Severe Wound :

Combination of :

1. Clumped platelets
2. Damaged cells
3. Clotting  factors in the plasma

Form the activator called Thromboplastin

It converts Prothrombin( inactive plasma protein)

With the present of :

1. Calcium ions
2. Vitamin K

To Thrombin(active plasma and act as enzyme)

With the present of :

1. Calcium ions
2. Vitamin K

This thrombin catalyses Fibrinogen(soluble protein) Fibrin (insoluble protein) :

-  mesh over the wound, trapped the red blood cells and sealing the woundto

Problems Related To Blood Clotting

Haemophilia :

1.  An inherited disease cause by a lack of particular Clotting factors in the blood.

2. A person may die due to excessive bleeding from minor cuts and bruises and also can cause spontaneous  internal bleeding.

Thrombosis

1. A process of clot formation inside an unbroken blood vessel

                 2. The clot is called thrombus

                 3.  A blood clot that travels in the bloodstream is called an embolus

                  4. Blood flow in the blood vessel will stop if the embolus

                      lodged in an artery and it can’t pass through it.